Spence Townsend earned his BFA in painting and drawing from the University of Southern Mississippi, and his MFA in painting and drawing from the University of Georgia. He works primarily with oil painting and screen printing and also explores the possibilities between art, music, and animation. He taught painting and drawing courses at the University of Georgia. Townsend was the manual screen printer at a graphics company in Hattiesburg, Mississippi. His art has been featured in group exhibitions at the Georgia Museum of Art and Rogue Space in New York City. His solo exhibitions include a 2016 show at the Lyndon House in Athens, Georgia, and a 2015 showing at Southside Gallery in Oxford, Mississippi. He has received numerous awards and grants such as the Wilson Center Graduate Research Award, the Tom Hollingsworth Art Scholarship Fund for Graduate Research, and The Mary Rosenblatt Graduate Scholarship. American Illustration published one of Townsend's pieces in their annual 2016 online anthology.